Revolutionaries and Self Martyrs Essay Example | Topics and Well Written Essays - 2750 words

Revolutionaries and Self Martyrs - Essay Example Revolutionary movements in the 1960s also included Palestinian groups like the Al Fatah and Popular Front for the Liberation of Palestine. Inspired by communism and supported by the USSR, they advocated a strategy of guerilla warfare and terrorism to liberate Palestine. The concept of people’s war was developed as Palestinian leaders understood that Muslim states were incapable of mounting any serious military opposition to Israel. Urban terrorist warfare was the goal of these movements as they learned about it from revolutionary movements in Palestine, Zimbabwe, Vietnam, China, Cuba and Algeria. The Palestinian network in the 1970s was the main financier and supporter of European, African and Latin American revolutionary movements. The late 1970s was a turning point as the Soviets invaded Afghanistan. Many Arab and Western governments began to recruit young people to wage a holy war against the Soviets. Another phenomenon was the rise of the Islamic revolution in Iran which b egan to view not only the US and Israel as enemies of Islam but also the Arab regimes. The 1980s saw the rise of Afghan groups who were bolstered by an influx of volunteers from the Muslim world and weapons from the West. Iran began to export its own revolution especially in Lebanon where it trained and armed Hezbollah. This group was responsible for the first suicide bombings and kidnappings against Western targets. Both Islamic fundamentalist and secular revolutionary movements have shared many similar goals.

Entrepreneurship and Small business ( MARKETING) Essay

Entrepreneurship and Small business ( MARKETING) - Essay Example This marketing environment can work to the advantage of the firm as well as become a real nuisance, more so when the economy is not that encouraging boosting trade ties between stakeholders, different organizations and so on and so forth. The corporate strategy plays a significant role at building a bridge between the company’s inner policies and the undertakings it has with the various stakeholders, who could be from the external marketing settings. (Korzeniowski, 2001) One should believe a small business is mostly at the mercy of the person who is responsible for running it. This small business is usually short of any expectations that the business fraternity might have of the same. The owner is the sole person who is responsible for funding the business regime and thus has a major stake within the running stakes. A small business is dependent on all the actions taken by the person in-charge and without his sound input this business would not see success touching its feet. The small business requires strict vigilance on a proactive basis. This vigilance must come from the owner himself since he is the one who will eventually face the brunt of the actions that he undertakes. (Bridge, O’Neill & Cromie, 2003) Also he must remain open to ideas from the people with whom he is conducting business as well as avoid litigation measures in order to exponentially increase on his returns and cutting down on his losses. Being vigilant would actually hel p him to shape up his troops in the times to come and he would have a better idea of running the business within the due course of time. Funds are essential for the sound running of any small business. If the owner does not have sound funding mechanisms in place, he will face a tough time when there is economic recession or when he has to pay the salaries to his employed staff. A small business cannot afford lapse

Calculation of Body Surface Area (BSA) for Blood Volume

Calculation of Body Surface Area (BSA) for Blood Volume CHAPTER 25 Calculation of Body Surface Area, Circulating Blood Volume,  Requirement of Blood Products Namita Mishra, Sudha Rawat, Vishva Nath Sharma BODY SURFACE AREA (BSA) Body surface area (BSA) is the area of the external surface of the body, expressed in square meters (m2). In physiology and medicine, the body surface area is the measured or calculated surface of human body. It is used to calculate metabolic, electrolyte, nutritional requirements, drug dosage, and expected pulmonary function measurements. BSA is a measurement used in many medical tasks. For many clinical purposes BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass. Nevertheless, there have been several important critiques of the use of BSA in determining the dosage of medications with a narrow  therapeutic index  like many chemotherapy medications. USES OF THE BSA To gain an appreciation of the true required glomerular filtration rate (GFR) renal clearance is usually divided by the BSA. To calculate a better approximation of the required cardiac output as for example in children, cardiac index is used. Cardiac output = Cardiac Index / BSA Chemotherapy is often dosed according to the patient’s BSA. Glucocorticoid dosing is also expressed in terms of BSA for calculating maintenance doses or to compare high dose use with maintenance requirement. CALCULATION OF BSA It is difficult to actually measure the surface area of the human body so various calculations have been published to arrive at the BSA without direct measurement. The most widely used is the Du Bois formula: BSA = 0.007184 X W0.425 X H0.725 A commonly used and simple one is the Mosteller formula: 0R BSA = ( [ H X W]/ 3600)1/2 Where H = Height W = weight for example : Patient’s weight = 65 Kg Patient’s height = 165 cm BSA = ([65 X 165])/3600)1/2 BSA= 1.72 m2 Recently, a weight-based formula was validated in the pediatric age group that does not include a square root, making it easier to use. It is [4Wkg+7]/[90+Wkg]. AVERAGE VALUES Average BSA for various weights: WEIGHT (Kg) BSA (m2) 1.5 4 0.13 – 0.26 4.1 – 9 0.26 – 0.48 9.1 – 14 0.48 – 0.56 14.1 – 20 0.56 – 0.71 20.1 – 26 0.71 – 0.84 26.1 34 0.84 – 1.0 34.1 – 50 1.0 – 1.4 50.1 66 1.4 – 1.63 Over 66.1 Over 1.63 EFFECTIVE CIRCULATING VOLUME Blood volume is the volume of blood (both red blood cells and plasma) in the circulatory system of any individual. A typical adult has a blood volume of approximately between 4.7 and 5 liters, with females generally having less blood volume than males. Blood volume (BV) can be calculated given the hematocrit (HCT; the fraction of blood that is red blood cells) and plasma volume (PV): BV = PV/ (1-HCT) Diagnostic technologies are commercially available to measure human blood volume. A recent radio nucleotide study called BVA (Blood Volume Analysis)-100, provides a measure of Red Blood Cells and Plasma with 98% accuracy. BLOOD VOLUME ESTIMATION WEIGHT (kg) BLOOD VOLUME ( ml/kg) New born to 10 85 11 to 20 80 21 to 30 75 31 to 40 70 Above 40 65 CIRCULATING VOLUME OF THE CPB CIRCUIT PRIMING VOLUME: the minimum amount of fluid (hemic or non hemic fluid) used to de- air the complete cardiopulmonary bypass (CPB) circuit is called priming volume or the circulating volume of CPB circuit. Priming of the CPB circuit is an important task for the perfusionist. Generally the main objectives of priming are: To deair the CPB circuit To check for any leaks in the circuit To check for any mistake in the assembling of the circuit To meet the need for the extra volume required to prime the CPB circuit as the patient’s blood volume is not sufficient enough to prime the CPB circuit. For achieving sufficient hemodilution. It is a standard practice to use a non blood CPB prime because of the benefits of hemodilution and concerns about blood borne diseases. The total priming volume is determined by the hardware selected for the circuit to be employed. Following are the tables showing the volume required to de-air various oxygenators, arterial filters and tubing. CPB CIRCUIT AND TOTAL PRIMING VOLUME WITH VARIOUS WEIGHT GROUP Weight Group (Kg) Boot Size (inches) Venous line Size (inches) Arterial line Size (inches) Total Priming Volume (ml) 0-4 1/4 1/4 1/4 450 4.1-8 3/8 1/4 1/4 600 8-12 3/8 3/8 1/4 800 12.1-25 3/8 3/8 3/8 1100 >25 1/2 1/2 3/8 1800 TUBING SIZE WITH VOLUME (ml/feet) SIZE (inch) VOLUME (ml/feet) 3/32† 1.8 1/8† 2.5 3/16† 5 1/4† 9.65 3/8† 21.7 1/2† 38.6 SPECIFIC CONSIDERATIONS: In cases where patient is deeply cyanotic the size of the oxygenator and tubing size is selected keeping in mind the requirement of higher degree of hemodilution and higher requirement of arterial blood flows because of the presence of large (or major) aorto-pulmonary collaterals (MAPCA’s). MAPCAs arise from the aorta or its large branches and supply blood to the pulmonary arteries, because of blockade of the main pulmonary arteries. These MAPCAs ‘steal’ part of the cardiac output of the aorta and this results in reduced systemic perfusion and thus increased pump flows are required during CPB in cyanosed patients with MAPCAs to compensate for this ‘stolen’ cardiac output. CACULATION OF BLOOD AND BLOOD PRODUCT REQUIREMENT The hematocrit (HCT), also known as packed cell volume (PCV) or erythrocyte volume fraction (EVF) is the volume percentage (%) of red blood cells in blood. It is normally about 45% for men and 40% for women. It is considered an integral part of a person’s complete blood count along with hemoglobin concentration, white blood cell count, and platelet count. Haemoglobin concentration is reduced as a normal consequence of CPB with hemodilution. Thus the hematocrit that will result from the hemodilution caused due to priming volume of the CPB circuit should be determined. Several calculations are required to assess hemodilution and blood product requirements. To determine the effects of hemodilution, the volume concentration formula is used. C1 X Pt BV = C2 X TVon CPB Where Pt BV = patient’s blood volume ( patient’s body weight X blood volume factor) TVon CPB = total volume on CPB (total priming volume + patient’s total blood volume) C1 = Pre bypass hematocrit of the patient (%) C2 = calculated hemodilutional hematocrit (%) A decision must be made initially regarding the desired hematocrit during cardiopulmonary bypass. Based on the results of the randomized clinical study from Children’s Hospital, Boston ,it seems reasonable to consider a hematocrit of 25% to be the minimal acceptable hematocrit for any cardiopulmonary bypass condition. When the desired hematocrit has been selected the amount of bank blood that must be added to the prime should be calculated. Prime RBC vol = {[C3]x[Pt BV + PV]} {Pt RBC vol} Where Prime RBC vol = volume of blood required in prime C3 = desired HCT on bypass Pt BV = patient’s blood volume ( patients body weight X blood volume factor) PV = total priming volume of the CPB circuit to be used Pt RBC vol = patient’s blood volume X patient’s pre bypass hematocrit For example: Patient’s weight = 5 Kg Pre bypass hematocrit (C1) = 40% Patients blood volume (Pt BV) = 5 X 85 = 425 ml (85 is blood volume factor for 5 Kg) PV (total priming volume of the CPB circuit to be used) = 600ml TVOn CPB = (600 + 425) = 1025ml Calculated hemodilutional HCT (%) (C2) = C1 X Pt BV / TVon CPB = 40 X 425 / 1025 = 16.5 % 16.5 is the hematocrit on bypass. If there is a certain desired hematocrit, then to achieve that hematocrit, the amount packed RBCs if needed for the same patient can be calculated as follows: C3 (desired HCT) = 30 % Pt BV = 425 ml PV = 600 ml TV On CPB = (Pt BV + PV) = (425 + 600) = 1025 ml Pt RBC vol = 425 X 0.40 = 170 Prime RBC vol = {[C3]X [Pt BV + PV]}-{Pt RBC vol} = {[0.30] X [1025]}-{170} = 137.5 Volume of RBCs needed in prime = 137.5 The hematocrit of packed RBCs is 70% thus 137.5/0.70 = 196 ml 196 ml of packed RBCs are needed to achieve a hematocrit of 30%. Thus, 196 ml of the clear prime fluid is removed from the priming volume to account for the added packed RBCs. Therefore the calculation of priming volume now has 196 ml of packed RBCs and 404 ml of prime (crystalloid or colloid). In some cyanotic cases where the patient’s pre bypass hematocrit is more, the blood is diluted to obtain an optimal hematocrit during cardiopulmonary bypass in order to decrease the viscosity of the blood to improve tissue perfusion and to prevent hemolysis. Thus the effect of priming fluid added to dilute the blood can also be calculated as: TVon CPB X C4 = TVon CPB 1 X C5 WHERE TVon CPB = total volume on CPB (total priming volume + patient’s total blood volume) = 1025ml C4 = Hematocrit (of cyanotic patient) on bypass = 0.60 TVon CPB1 = total volume on CPB after adding 500 ml of priming fluid to the CPB circuit. TVon CPB1 = (1025 + 500) = 1525 ml C5 = the new (affected) Hematocrit Thus C5 = (1025 X 0.60) / 1525 = 0.40 40 % is the new hematocrit achieved after adding 500 ml of priming fluid. FIBRINOGEN A critical consideration is plasma fibrinogen dilution. Normal plasma fibrinogen levels are 150-400 mg./dL. The infant/ pediatric patients relative low blood volume with priming requirements of the ECC circuit causes the fibrinogen concentration to be adversely diluted. During CPB, it is desirable to maintain the plasma fibrinogen concentration above 100 mg./dL. in order to prevent impairment of post-CPB hemostasis. Given an example of a 5 Kilogram patient with blood volume of (5 x 85) 425 ml, pre bypass hematocrit of 55%, hematocrit on CPB of 25%, priming volume of 800ml of the circuit to be used for CPB and fibrinogen level of 275 mg/dl. To calculate the effect of priming, patient’s plasma volume is calculated by following formula: BV = PV/ (1-HCT) PV = (1-HCT) X BV Thus PV = (1-0.55) X 425 = 191ml PV = 191ml Patient’s fibrinogen = 191 X 275 mg/100ml = 525 mg Number of milligrams required = (425 + 800 ) X (1.00-0.25) = 9.19 dl If the goal is 100mg/dl, then 919 mg of fibrinogen are needed. Amount of fibrinogen to be added = 919 – 525 = 394mg. 394 mg of fibrinogen must be added to the prime to achieve a goal of 100 mg per dl. FFP usually contains 200 mg of fibrinogen per dl. Thus ml of FPP needed = (394/200) X 100 = 197 ml. Now for the calculation of priming volume the 197ml of the prime fluid (crystalloid or colloid) is replaced by FPP. Thus the clear prime volume becomes 603ml. Suggested reading Jianfeng Wang, Eiji Hihara. A unified formula for calculating body surface area of humans and animal. Eur j Appl Physiol.2004;92:13-17 Dill DB, Costill DL. Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J. Appl. Physiol. 1974; 37(2):247-248. Tarazi RC .Pulmonary blood volume. Eur Heart J.1985Oct;6SupplC:43 Tarazi RC . Blood volume.. Eur Heart J.1985;6SupplC:41-42

Holes Essay

Novels are extremely important part in people’s life. They teach us valuable lessons and provide an escape from the real world. Louis Sachar’s novel Holes, allows teenagers to feel for the characters and also allows them to relate to what character is going through. In the novel Holes, there are many characters that teenagers can relate to. One of these characters is Stanley. Stanley is the main character from the novel. When he first arrives at Camp Green Lake Stanley was bullied by the inmates and put in his place. He soon became friends with the inmates from group D. Everyone in group D had a nickname. Stanley had yet to get one but when he was called Caveman for the first time he finally felt that he was accepted into the group. â€Å" you coming caveman? Said squid. Stanley looked around to see that armpit and squid were talking to him†. Another character from the novel that teenagers can relate to is Zero. Zero is a small, shy character who Stanley becomes great friends with in the beginning of the novel. When Zero became friends with Stanley, the reader learnt that Zero is silent because he does not like answering questions because he is cautious of people like Mr. Pendanski, who always mock him. Teenagers can relate to this because they are always wary of what people think about them. Zero was called stupid and dull all the time which makes Zero angry but he can’t do anything about it because he is a lot smaller than the rest of the inmates. â€Å"He is so stupid he doesn’t even know he is stupid†. Zero represents an incompetent teenager that we can all relate to at some point in our life. Louis Sachar uses many themes in the novel Holes. One of these themes is friendship. The benefits of forming solid friendships are clearly shown in the text. Stanley and Zero’s friendship leads to survival and wealth. Once Stanley became Zero’s friend he feels happier than he has ever felt in his life. False friends who are only friendly when they are getting something they want, like X-Ray, are shown to be dangerous. Once X-Ray stops getting benefits out of his friendship with Stanley, he becomes hostile towards him. â€Å" Another very important theme from the novel is Bullying. Bullying is used throughout the novel, which helps teenagers feel and understand what the characters are going through. Bullying is the act upon a person or persons causing harm physically or mentally. This theme adds extra emotion to the novel. The two characters Zero and Stanley are used to generate an authentic and recognisable aspect in the book. Stanley and Zero bond throughout the text and Sachar modifies the language when they are present to relax the reader, so they can interpret the text in their own way this quote clearly describes the beginning of their friendship and allows the reader to warm up to the characters. Conclusion Louis Sachar uses all these techniques to create a fascinating novel that all teenagers can relate to. Sachar uses language techniques appropriately and it enhances the books attractiveness and makes teenagers continue to read the book

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Killing of Dolphins - Free Essay Example

Sample details Pages: 2 Words: 452 Downloads: 6 Date added: 2017/09/13 Category Advertising Essay Did you like this example? Here is the topic: Many people in Japan strongly believe that hunting dolphins has been a  part of the culture, and non-Japanese cannot criticize their practice. Their opinion is that many Westerners eat meat, so they are being hypocrits for criticizing Japanese for eating another kind of meat. Do you agree with Japanese, or do you disagree? What are your reasons for your opinion? I strongly disagree. Don’t waste time! Our writers will create an original "Killing of Dolphins" essay for you Create order * Dolphins have very high mercury levels * Mercury is a known cause of birth effects In 2010, hair samples from 1,137 Taiji residents was tested for mercury by the National Institute for Minimata Disease. The average amount of methyl mercury found in the hair samples was 11. 0 parts per million for men and 6. 63 ppm for women, compared with an average of 2. 47 ppm for men and 1. 64 ppm for women in tests conducted in 14 other locations in Japan. * The Japanese town of Taiji on the Kii peninsula is as of now the only town in Japan where drive hunting still takes place on a large scale. In 2007 Taiji wanted to step up its dolphin hunting programs, approving an estimated ? 330 million for the construction of a massive cetacean slaughterhouse in an effort to popularize the consumption of dolphins in the country * an increase in criticism and the considerable toxicity of the meat appears to be achieving the opposite * Taijis bid to expand their school lunch programs to include dolphin and whale meat brought about much controversy. An estimated 150  kg (330 lbs) of dolphin meat was served in Taiji school lunches in 2006. In 2009, dolphin meat was taken off school menus because of the contamination * Dolphins are top predators in Japan * Primary or apex predators can actually benefit prey populations by suppressing smaller predators, and failure to consider this mechanism has triggered collapses of entire ecosystems. * Cascading negative effects of surging mesopredator populations have been documented for birds, sea turtles, lizards, rodents, marsupials, rabbits, fish, scallops, insects and ungulates. The economic cost of controlling mesopredators may be very high, and sometimes could be accomplished more effectively at less cost by returning apex predators to the ecosystem. * Human intervention cannot easily replace the role of apex predators, in part because the constant fear of predation alters not only populations but behavior of mesopredators. * Large predators are usually carnivores, but mesopredators are often omnivores and can cause significant plant and crop damage. The effects of exploding m esopredator populations can be found in oceans, rivers, forests and grasslands around the world. * Reversing and preventing mesopredator release is becoming increasingly difficult and expensive as the worlds top predators continue to edge toward obliteration * We aren’t attacking their belief, dolphins are top predators and as a result messes with the ecosystem; plus they contain high mercury levels which cause

Hidalgo, The Existential Struggle Of Faith And Reason

Miguel Hidalgo (Hidalgo) was a foremost a man, and secondly a priest. He did not like to be controlled by outside forces, but forcibly conceded to working under the watchful eye of the Catholic Church. Through this predicament, Hidalgo was presented with many conflicting ideas regarding the importance of faith of which the standards were set by the Catholic Church, and reason, which was influenced, by the ideas of the Enlightenment. Hidalgo, the historical character is presented as being someone who saw the great conflict in these ideas, and saw that the only way to crown a victor was through warfare. However, the character of Hidalgo in Hidalgo: La Historia Jamas Contada actively sought peaceful ways to have both ideas of faith and reason coexisting in the same society, in different ways, for different people. In the film Hidalgo: La Historia Jamas Contada, the character of Hidalgo is faced with the existential struggle of faith versus reason depicted in his journey from priesthood to revolutionary, during which the flame of Hidalgo’s tendency, throughout the film, to accept and emulate the abnormal for society in that day was lit, ultimately leading to the start of his revolution. The time in which Hidalgo was beginning to wage his internal war marked a period of great power for the Catholic Church and the Spanish monarchy due to their extreme influence on each other. These governing bodies expected their subjects to act in a certain manner, and confined them to the